SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd369e1e40975d211303d56925bade7e3b7111c0da2165cfa3d316a8ca3f27b45' 
  AND token = 'GRD/QNODukSOEXrw2k1chKrXBISi6RJcl4e9Qi8xqZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}