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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0114687addfcb1342f1a39f023388844632e71b4f35fa63b7f7b6bc89ddcb468' 
  AND token = 'qUMfsU+3GNO4pASaprmYEmYkqhb0pQnvbG9C/7N6cRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}