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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a49e6b4c99a41e5697bfd5b74e3974707317e887c9ac6b16719ef571e393de2' 
  AND token = 'vT/AG2zk62xeBAjvfcZezu2L311VU/xh3oqmvWBgoxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}