SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe2ba182d158df4daecc6bd8b422ddc9b43cfd7dc98a6bed741e308e2f192b9' 
  AND token = 'AXQdYmbrTfpFlmwLFlu24aPOrrdbWI7qIK2bs9Uo9zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}