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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f7b9e65fe65be12656a340e9e48660d3b29d358930fe3d1a159cda67655028' 
  AND token = 'NsK7+CWYxdY1y0F0Iz+yTs45GOWPnYbF2pPKRW3iVgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}