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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e999eacc612f78304a0c11975f6e2cc8e1cbb77b49e96640dacc64508e1361' 
  AND token = 'ViTAt0IuzPsbLpK5ihreJ7j3plESRYtBZiRTImZm0RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}