SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f321d227e3cfa6dabf1fa3f8566fcabbaaeb8021a2bb1e83cfb611cf9291743c' 
  AND token = '3UHx6HNQmctroUL0t7JxBJvk9JevY5uIPxt/PLmhSPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}