SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf75eb23b97a19e59f680f680553cbc88aa62d6cb01646c63618705fd3bbd71' 
  AND token = 'ctkgkiXZmOEMNdEFXIeNfSwoxgrcHcRqChdHGPq486M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}