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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e172c3a94223a7adbb39737d86022c897d646e3bda2849887831606506e6b3' 
  AND token = 'aM4VtULkXLmOg9q1KaB+6OP8kbd6fe9AwQ3/PFW5g/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}