SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b29b174b2511ac38f1bbf9678ee0a5a3897c050dd8dffc2f009c534fbfe453e' 
  AND token = 'XqaVmJPASH/R+X7BrR4F9iQ/oRihVrrH9bNQUfAvmfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}