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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0ed29fba69acbf6b54e1034a001e6ac78149ca79af1b8d66680a5bdb60f495' 
  AND token = 's+MKWVXOtVA/m/E51nyWz8hGfCyyBghP5GQMozrt4f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}