SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd1beeab10b7131e7ef0c76e4aa00e90210b63a39c5605c06a0401d620bad686' 
  AND token = 'as3OZIP7oJR7ndfascv8Jk0JOSdh99JKdOpencPgPL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}