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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4482709ec8fb800bfca3748f22e49494cdc5f8f7e4ae41ef1c65df0a4d2cacb6' 
  AND token = 'ihHmOcrT7MrfKPQZRTHd7vlE7WUEaump3lGWfzhjJL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}