SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e5dba4543ba7d2da4310858d8dec1b2fad748af47261a23fb0e0cfaec6cb34' 
  AND token = '/hdyZ3b6+XIHh246fIEIDCtc8CpVcB2JD0lXdTUMme4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}