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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fbd41cb521c085a882af87d416e46c78aee81a0c3ed3d804b88ffc607a364b9' 
  AND token = 'UTTJUWP34SqZufdIJ+WiNQ2mLwOKbE0j3EbNH0guwEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}