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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e4c1b13b4ee6a93332ae85122e905696e20860029db8080868f7a52c1b20b3' 
  AND token = 'Dg/9fJGwu/iDL5GQVM6zOWi87N8lHLebIW88G8+Q7BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}