SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b154e998a0594598d04f409b4a323dec98848e4dd1d3091792a6b3617a5cbc' 
  AND token = 'icMY8ffGy3CNCVz/QB52BkRzc2voUayfg2TG3beHKVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}