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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ace9a83cf6f87375a3fb5b4c3d1d1f6dab25660ed63ed072f5653de5cd4ade0' 
  AND token = 'X9AQn0ql6HUxXJmoiPpgIaJUQBpPLRM9DZaETonEhTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}