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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2944828bcd92b380a4f26f87086ef68460feb04a9052b0db63abb08c228162' 
  AND token = 'FDaIQYfTI+WzpfhE6VSD58V2UPbyvbwzmytbXvncgkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}