SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e5332401bb6b20e9fdb0807ae27365fbfff2195769a33c05814c7ea0b9e5ac' 
  AND token = 'MpOrHDPGzVfoMgeQBued/qH6gUqSvdAxOFz9PG/mhvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}