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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4165e6dbd0b7c5269b94a30b20281be6c2028ff5773cc83eb424bb014cb737cd' 
  AND token = 'md/ApqPlCNXUOUK8qpI8Gn1/Mdm8ncT4MRRzkrYG5AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}