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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b460163abfde6cf1d6dee02e1043d24ebe18086bb2e9163b91a8ab402ddadeb3' 
  AND token = 'uzTF7cEQUzkGRV1fvXKP6DBXkq7rG3KiPkewoF7GZGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}