SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e142cc926260482bb176fc5dc02ce7fba3d97b975b67904318825c7e4eee2f' 
  AND token = 'pmfsirAKLEyTSf2Jtku0Idl56UFlVSLwmUCWr1zwkL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}