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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9043da2d985012fa443c16bcb0d5ff6fa35f48bdabcafc09548ca72cffbf6c34' 
  AND token = 'UqDhm0CAgOtckNm4MEiS9AWISJeF80XPID2skCp6gD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}