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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5827951336f1cd4defe476abeea01e4b01a4ac42248ef144357a07e1b2821513' 
  AND token = '96kKYYnKpIYYrushhZMBaAN/Sq81CaZgzxryST2De/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}