SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ca78fb6f83a8eaccb85b816d63ab9669cb2f10384698c7fb2046ebc77a577d' 
  AND token = 'LCTVkH1wkJtYOJCqGimVTqqeqOEDslnNHndEbGYm/qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}