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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83dc0b225725f734f5cba017cd8d8ae54247a6fa8b7dddf8f35d86eb05f801e6' 
  AND token = 'uWhEoD/DMLCvanAOuTbQj8l8jFWrvKvHK9iJ5ZGN7sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}