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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f67eb64027fefb27482f5e2813e1d0fce0fcd6fe77c78d459c7725957464fb' 
  AND token = 'rQrVyKD2x9knlG8UcHpVu6nNhdVV0Ap4PV7y8eQaukQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}