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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452cb54f15924dbc0bf4741c6e93d5344cf7bbe148b27fdc17be5c92512c26aa' 
  AND token = 'y0Oy/ZhDTCn6AmNJP0XN/08gOaE4mxGezQp5wVN6Qok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}