SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1592856bca1279ae039ff130534ec71d366e56b5bf7bcbe70cf03f13b3c59a90' 
  AND token = '28+iz5Rn1iEqyvlLu2Emnbzlt6P3cY+mrtCzcWcpwb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}