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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53b15594c24d63323df3f5ed59a01b3d41262269a7592aedbc5a4a0e6b88a05' 
  AND token = '1n++nmN0g2/OppkpYhwzAeNn7MIYBBPJOp5JESG/3hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}