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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2350994a61c20b30589d97560547a2a228403cc7f328f73d2f5c3d4db23aa1a2' 
  AND token = 'fz/I/Dlp3Ye2Im+GCdehOSl8G4gMJVEvubI226w/XVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}