SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dbcaeaf6987d2ac99df11029be7a719a1ca0177805293ff3c5fd0c03f1b78a2' 
  AND token = 'HVbQgVMSOz89aRxONK/C2jvI8jL14mlE+WH1qSVI15s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}