SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e2948ea0de4cde8f3a73cd6c17745ec166eac4ecf3f7c6f24af9ccaf998e86' 
  AND token = 'fusFSBa52+ac68cNp+/Y7SF3zUPX4rMQZ40dKu6RMLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}