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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b152a207bfa7585cbbd42336a5761f268be3e443b001f521c06285668264f5' 
  AND token = 'QMrDw9osnUFviNbGUgeDQnUL5m0LBDWQVfX/Niob5dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}