SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33eea7b0ec792eec37a9e96be74f09a960d19150f6f9149a7d1dfc0194039302' 
  AND token = 'bXvf4z1vciL+iMOK1VV3mIR32VpkNwgP+HvD8s//IWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}