SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8fb9fcea74535580d536e3484bb8addb96abc2c225b75e15fe24a30a8587f6e' 
  AND token = '+2w84n5SuUW697nwMJnG2+EQUuvNYQ7xrlmgh/R32No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}