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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4078107b7d07e0e119c4ec561464b80e11a3639ebcfbb56c762c7750e8b79816' 
  AND token = 'E3VHvuWAm1BhnwqnPyqLlT0b2jWQF82vEeR/A6ud3cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}