SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0478676da375a97fdc186438472ef8bd70f92d741cf6338ca03459b19aefde53' 
  AND token = 'njBOsBQdmUgwTyE5ibaQHbhWf8xVBNExROyzQWMnctY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}