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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3815f4d3950b8af31fab5c4c65f9f668a171ac1a7185f0e802bffb19d95f40b2' 
  AND token = 'NL8X8wUvNrHUYPw0YlCIRUk8i+AmywvZ6UeZagjhzxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}