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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e636deca892c0075cbc437b5f84a0d2330c3662ca3291e73f0bc2ab4797c254' 
  AND token = 'Karw/nkaMClfzVecfJDxM73OKDSC03P1Hdp9mHQAcMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}