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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b26ea9eb6f4254e3b7f84d05066737f541a8d8389924a7baaf798f7bc8cc881' 
  AND token = 'wznpLu/vRadDdx6DRRfRZPTD61rutcF/C7vA/x3aPhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}