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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acbe1ddf6da0fe212e255a2b04cee3751501b940c28b9eadaaf4aedb3d5e513' 
  AND token = '7dL0LD2sw9n1uXXGDp+yaextDb8e3sf/yhf7TuNXc4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}