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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e60093d43948fa02c098533352ad0b62b0aa9b3a2667e4ad0853d2cb40eb44f8' 
  AND token = 'm4w2TYSIazSuDHg1Nf5ybnN+6cL3Xy51KPtNVz/KURI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}