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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50194225a1aa7820dfa2b78290d02621e5aa70bafd11ad9ff14c4d13b8379e05' 
  AND token = '3rWuXABfdGLFhzWCPMoJWL89Ehzvwv7DoPreH2URfX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}