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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4fc902de92afd597f51b02193b83f81e6340a9b141419b334a2efdca5c8a7b' 
  AND token = 'g7hVecU8Wf/Fu8ohp+aGF6UX8UWJvc6beNPAVY3Aa9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}