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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e5a981f66406d39fbf3c5505152904676def3dadb8b47d7aaa74f5b6248e8f' 
  AND token = 'iJ4JeWCCio4/RqHaIBlyZru2yc9Ol6/am0Uo0x9RZXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}