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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485072b76130315cffc8be371e7e301530461de295b3e7c0fa3acf4e58bac263' 
  AND token = 'g8wmhxvZz0NWk0IqQA+TUXayrHXOaxsvsQcg+EA1BO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}