SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e6e00b2e0f22c3567fb6633eb0746391aa1cf0b6763a2fd637f4d8bfd7f57d' 
  AND token = 'nZjLuB83iX8fLdtbRAPIJG1emyC19dNHBLZVk7jw8x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}