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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b28467e266c4e2ea124f8804ef71f2fb034838922d4aa5b0de749ec0dfe3033' 
  AND token = 'pzaGaFYaBexam+tHA7zNHHpRbmrDZ2wcK1ECouAclF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}